Cognitive and behavioral dysfunction in Parkinson’s disease: neurochemical and clinicopathological contributions

@article{Zgaljardic2004CognitiveAB,
  title={Cognitive and behavioral dysfunction in Parkinson’s disease: neurochemical and clinicopathological contributions},
  author={Dennis J Zgaljardic and Nancy S. Foldi and Joan C. Borod},
  journal={Journal of Neural Transmission},
  year={2004},
  volume={111},
  pages={1287-1301}
}
The cognitive and behavioral sequelae (i.e., nonmotor profile) of Parkinson’s disease (PD), with executive dysfunction and depression being most prominent, have typically been overshadowed due to an emphasis on motor symptomatology. The apparent categorization of PD as a disorder isolated to the dopaminergic system may be a generalization of the disease pathology. Dopamine therapy, used for the treatment of motor symptoms, has not consistently been shown to resolve nonmotor impairments… CONTINUE READING