Cognitive and Clinical Dysfunction, Altered MEG Resting-State Networks and Thalamic Atrophy in Multiple Sclerosis

@inproceedings{Tewarie2013CognitiveAC,
  title={Cognitive and Clinical Dysfunction, Altered MEG Resting-State Networks and Thalamic Atrophy in Multiple Sclerosis},
  author={Prejaas Tewarie and Menno M. Schoonheim and Cornelis J. Stam and Marieke L. van der Meer and Bob W. van Dijk and Frederik Barkhof and Chris H. Polman and Arjan Hillebrand},
  booktitle={PloS one},
  year={2013}
}
The relation between pathological findings and clinical and cognitive decline in Multiple Sclerosis remains unclear. Here, we tested the hypothesis that altered functional connectivity could provide a missing link between structural findings, such as thalamic atrophy and white matter lesion load, and clinical and cognitive dysfunction. Resting-state magnetoencephalography recordings from 21 MS patients and 17 gender- and age matched controls were projected onto atlas-based regions-of-interest… CONTINUE READING
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