Cognitive abilities in children with congenital muscular dystrophy: correlation with brain MRI and merosin status.

@article{Mercuri1999CognitiveAI,
  title={Cognitive abilities in children with congenital muscular dystrophy: correlation with brain MRI and merosin status.},
  author={Eugenio Mercuri and J Gruter-Andrew and J W Philpot and Caroline A. Sewry and Serena J. Counsell and Scott H Henderson and A. P. Jensen and Isam S Naom and Graeme M. Bydder and Victor Dubowitz and Francesco Muntoni},
  journal={Neuromuscular disorders : NMD},
  year={1999},
  volume={9 6-7},
  pages={383-7}
}
The aim of the study was to evaluate whether children with merosin-positive or merosin-deficient congenital muscular dystrophy (CMD) show any cognitive impairment and whether this is related to brain abnormalities on magnetic resonance imaging (MRI). Twenty-two patients (age range: 5.8-15.3 years) were assessed by the Wechsler Intelligence Scales. Twelve were merosin-positive and ten merosin-deficient. One child had severe mental retardation and could not be tested. The full scale IQ in the… CONTINUE READING

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