Cognitive Stimulation Modulates Platelet Total Phospholipases A2 Activity in Subjects with Mild Cognitive Impairment

@inproceedings{Balietti2016CognitiveSM,
  title={Cognitive Stimulation Modulates Platelet Total Phospholipases A2 Activity in Subjects with Mild Cognitive Impairment},
  author={Marta Balietti and Cinzia Di Giuli and Patrizia Fattoretti and Paolo Fabbietti and Demetrio Postacchini and Fiorenzo Conti},
  booktitle={Journal of Alzheimer's disease : JAD},
  year={2016}
}
We evaluated the effect of cognitive stimulation (CS) on platelet total phospholipases A2 activity (tPLA2A) in patients with mild cognitive impairment (MCI_P). At baseline, tPLA2A negatively correlated with Mini-Mental State Examination score (MMSE_s): patients with MMSE_s <26 (Subgroup 1) had significantly higher activity than those with MMSE_s ≥26 (Subgroup 2), who had values similar to the healthy elderly. Regarding CS effect, Subgroup 1 had a significant tPLA2A reduction, whereas Subgroup 2… CONTINUE READING