Cognitive Sequelae of Intravenous Amphetamine Self-Administration in Rats: Evidence for Selective Effects on Attentional Performance

@article{Dalley2005CognitiveSO,
  title={Cognitive Sequelae of Intravenous Amphetamine Self-Administration in Rats: Evidence for Selective Effects on Attentional Performance},
  author={Jeffrey W. Dalley and David E. H. Theobald and David M. Berry and Jean A. Milstein and Kristjan L{\"a}{\"a}ne and Barry J. Everitt and T W Robbins},
  journal={Neuropsychopharmacology},
  year={2005},
  volume={30},
  pages={525-537}
}
Characterizing the nature and severity of cognitive deficits associated with chronic stimulant abuse may provide new insights into the neural substrates of drug addiction because such deficits may contribute to the chronic relapsing nature of compulsive drug use. This investigation examines in rats the long-term cognitive consequences of intravenously self-administered amphetamine, specifically on performance of a 5-choice serial reaction time task (5-CSRTT), which assesses visuo-spatial… CONTINUE READING

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