Cognitive Impairment and Memory Loss in Diabetes: A Myth or Reality

  title={Cognitive Impairment and Memory Loss in Diabetes: A Myth or Reality},
  author={Madeeha Malik and Sidra Bi and Azhar Hussain},
  journal={Journal of Pharmacy Practice and Community Medicine},
Diabetes itself might not be a risk factor but mismanagement and poor control of disease may lead to the problem. High blood glucose levels, elevated blood pressure, obesity and high cholesterol collectively lead to complications including decline in cognitive ability. The present study was designed to explore the factors effecting cognitive impairment and memory loss among diabetes patients in twin cities of Pakistan. A descriptive cross-sectional study design was used. A pre-validated data… Expand


Predictors of cognitive impairment in type 1 diabetes
The major finding was that long diabetes duration and young age of diabetes onset were the strongest predictors of low scores in psychomotor speed, memory, processing speed, attention, working memory, verbal ability, general intelligence, executive functions and a low global score. Expand
Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia.
Among well-functioning older adults, DM and poor glucose control among those with DM are associated with worse cognitive function and greater decline, which suggests that severity of DM may contribute to accelerated cognitive aging. Expand
Diabetes mellitus: A risk factor for cognitive impairment amongst urban older adults
There is a weak association between diabetes mellitus and cognitive impairment amongst urban older adults and these subjects were divided into two groups with and without cognitive impairment. Expand
Increased risk of cognitive impairment in patients with components of metabolic syndrome
Cognitive decline was correlated with each of the constituents of Mets, which included high plasma glucose, elevated blood pressure, abdominal obesity, and decreased high-density lipoprotein cholesterol, with the exception of high triglyceride levels. Expand
Risk Factors of Cognitive Impairment and Brief Cognitive Tests to Predict Cognitive Performance Determined by a Formal Neuropsychological Evaluation of Primary Health Care Patients.
The addition of the MoCA, in persons with positive TRS scores, is a useful approach to improve the diagnosis of CI for at-risk patients attending primary health care. Expand
Risk of dementia in diabetes mellitus: a systematic review
The findings of mechanistic studies suggest that vascular disease and alterations in glucose, insulin, and amyloid metabolism underlie the pathophysiology of dementia, but which of these mechanisms are clinically relevant is unclear. Expand
Evaluating the Association between Diabetes, Cognitive Decline and Dementia
  • O. Ojo, J. Brooke
  • Medicine
  • International journal of environmental research and public health
  • 2015
There is evidence of the association between diabetes, cognitive decline and dementia including the shared pathogenesis between diabetes and Alzheimer’s disease, and the self management of diabetes is affected by dementia and cognitive decline. Expand
Cognition and diabetes: a lifespan perspective
This Personal View investigates the hypothesis that clinically relevant diabetes-related cognitive decrements mainly occur at two crucial periods in life: when the brain is developing in childhood, and when thebrain undergoes neurodegenerative changes associated with ageing. Expand
Diabetes and cognitive dysfunction
Disconcertingly, the rapid rise in obesity and type 2 diabetes in all age groups might result in a substantial increase in prevalence of diabetes-related cognitive dysfunction. Expand
Effects of Diabetes Mellitus on Cognitive Decline in Patients with Alzheimer Disease: A Systematic Review.
Current evidence indicates that the link between diabetes and cognitive decline in patients with AD is uncertain, and further clinical studies are needed, with larger samples, long-term follow up and an extended battery of cognitive assessments. Expand