Cognitive Effects of Intentional Weight Loss in Elderly Obese Individuals With Mild Cognitive Impairment.

@article{Horie2016CognitiveEO,
  title={Cognitive Effects of Intentional Weight Loss in Elderly Obese Individuals With Mild Cognitive Impairment.},
  author={Nidia Celeste Horie and Val{\'e}ria Trunkl Serrao and Sharon Sanz Simon and Maria Rita Polo Gasc{\'o}n and Alessandra Xavier Dos Santos and Maria Aquimara Zambone and Marta Merenciana Del Bigio de Freitas and Edecio Cunha-Neto and Emerson Leonildo Marques and Alfredo Halpern and Maria Edna de Melo and M{\'a}rcio Corr{\^e}a Mancini and C{\'i}ntia Cercato},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2016},
  volume={101 3},
  pages={1104-12}
}
CONTEXT Obesity in midlife is a risk factor for dementia, but it is unknown if caloric restriction-induced weight loss could prevent cognitive decline and therefore dementia in elderly patients with cognitive impairment. OBJECTIVE To evaluate the cognitive effect of intentional weight loss in obese elderly patients with mild cognitive impairment (MCI), considering the influence of age, apolipoprotein E (APOE) genotype, physical activity, biochemical markers, and diet. DESIGN Single-center… CONTINUE READING
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