Cognitive Dysfunction in Fmr1 Premutation Carriers.

  title={Cognitive Dysfunction in Fmr1 Premutation Carriers.},
  author={Andreea L. Seritan and Jennifer B Cogswell and Jim Grigsby},
  journal={Current psychiatry reviews},
  volume={9 1},
Premutation carriers of the fragile X mental retardation gene (especially men) older than 50 may develop a neurodegenerative disease, the fragile X-associated tremor/ataxia syndrome (FXTAS). Carriers may present with varied cognitive impairments. Attention, working memory, declarative and procedural learning, information processing speed, and recall are among the cognitive domains affected. Executive dysfunction is a prominent deficit, which has been demonstrated mostly in men with FXTAS. In… CONTINUE READING

Similar Papers

Loading similar papers…