Cognitive Control as a 5-HT1A-Based Domain That Is Disrupted in Major Depressive Disorder

@inproceedings{Langenecker2019CognitiveCA,
  title={Cognitive Control as a 5-HT1A-Based Domain That Is Disrupted in Major Depressive Disorder},
  author={Scott A Langenecker and Brian Mickey and Peter Eichhammer and Sukanta Sen and Kathleen Hazlett Elverman and Susan Elizabeth Kennedy and Mary Margaret Heitzeg and Saulo Rodrigo Lucas Ribeiro and Tiffany Marie Love and David T. Hsu and Robert A. Koeppe and Stanley J. Watson and Huda Akil and David Goldman and Margit Burmeister and Jon-Kar Zubieta},
  booktitle={Front. Psychol.},
  year={2019}
}
Heterogeneity within Major Depressive Disorder (MDD) has hampered identification of biological markers (e.g., intermediate phenotypes, IPs) that might increase risk for the disorder or reflect closer links to the genes underlying the disease process. The newer characterizations of dimensions of MDD within Research Domain Criteria (RDoC) domains may align well with the goal of defining IPs. We compare a sample of 25 individuals with MDD compared to 29 age and education matched controls in… CONTINUE READING

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