Cognition and memory impairment attenuation via reduction of oxidative stress in acute and chronic mice models of epilepsy using antiepileptogenic Nux vomica.

@article{Mishra2020CognitionAM,
  title={Cognition and memory impairment attenuation via reduction of oxidative stress in acute and chronic mice models of epilepsy using antiepileptogenic Nux vomica.},
  author={Priya Mishra and Amit Mittal and Satyendra K. Rajput and Jitendra Kumar Sinha},
  journal={Journal of ethnopharmacology},
  year={2020},
  pages={
          113509
        }
}

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Preventive Effects of Sinigrin Against the Memory Deterioration in the Pentylenetetrazole-Kindled Male Wistar Rats: Possible Modulation of NLRP3 Pathway.

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Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage

The results indicate that the chronic administration of NP-OTs may have positive effects on hippocampal damage via increasing neurogenesis and decreasing apoptosis and seizure severity and that OTs and NP-OTS had protective effects against PTZ-induced damage to hippocampal neurons.

Aqueous extract of Parkia biglobosa (Jacq.) R. Br. (Fabaceae) exerts antiepileptogenic, anti-amnesic, and anxiolytic-like effects in mice via mechanisms involving antioxidant and anti-inflammatory pathways

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PTZ kindling model for epileptogenesis, refractory epilepsy, and associated comorbidities: relevance and reliability.

The potential of PTZ kindling in mice and its modifications for its face, construct, and predictive validity to screen antiepileptogenic drugs, combined or add on novel and safe therapies for treatment of epilepsy-associated depression and cognitive impairment as well as effective interventions for pharmacoresistant epilepsy are summarized.

Pharmacological and Therapeutic Approaches in the Treatment of Epilepsy

The roles played by various neurotransmitters and their receptors in the pathophysiology of epilepsy are discussed and different non-conventional therapeutic strategies, including combination therapy and non-drug treatment are discussed.

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