Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study.

@article{Pike2011CognitionAB,
  title={Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study.},
  author={Kerryn Elizabeth Pike and Kathryn A. Ellis and Victor Villemagne and Norm M. Good and Gael Ch{\'e}telat and David Ames and Cassandra Szoeke and Simon M Laws and Giuseppe Verdile and Ralph N. Martins and Colin L. Masters and Christopher C. Rowe},
  journal={Neuropsychologia},
  year={2011},
  volume={49 9},
  pages={2384-90}
}
The 'preclinical' phase of Alzheimer's disease is a future target for treatment, but additional research is essential to understand the relationship between β-amyloid burden and cognition during this time. We investigated this relationship using a large sample of apparently healthy older adults (N=177), which also enabled examination of whether the relationship differed according to age, gender, years of education, apolipoprotein E status, and the presence of subjective memory complaints. In… CONTINUE READING