Cognition Enhancers in Age-Related Cognitive Decline

  title={Cognition Enhancers in Age-Related Cognitive Decline},
  author={Wim J. Riedel and Jelle Jolles},
  journal={Drugs \& Aging},
SummaryA review of recently published studies on the effect of cognition enhancers in non-demented human study participants is presented. The heterogeneity of the therapeutic target, age-associated cognitive decline, can be improved by separately treating groups in whom age-extrinsic factors may underlie cognitive pathology. Standardisation of cognitive assessments is necessary, since many different tests are applied to answer the same question. Modelling cognitive dysfunction, either by… 
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The assessment of cognition enhancers in the clinic is a broad topic that can be addressed from both academic/theoretical and therapeutic/drug development perspectives and it is necessary to utilize larger numbers of subjects and longer-term studies.
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