Coffee consumption rapidly reduces background DNA strand breaks in healthy humans: Results of a short-term repeated uptake intervention study.

@article{Bakuradze2016CoffeeCR,
  title={Coffee consumption rapidly reduces background DNA strand breaks in healthy humans: Results of a short-term repeated uptake intervention study.},
  author={Tamara Bakuradze and Roman Lang and Thomas Hofmann and Dorothea Schipp and Jens Galan and Gerhard Eisenbrand and Elke Richling},
  journal={Molecular nutrition & food research},
  year={2016},
  volume={60 3},
  pages={682-6}
}
SCOPE Intervention studies provide evidence that long-term coffee consumption correlates with reduced DNA background damage in healthy volunteers. Here, we report on short-term kinetics of this effect, showing a rapid onset after normal coffee intake. METHODS AND RESULTS In a short-term human intervention study, we determined the effects of coffee intake on DNA integrity during 8 h. Healthy male subjects ingested coffee in 200 mL aliquots every second hour up to a total volume of 800 mL… CONTINUE READING

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