Coffee consumption during pregnancy and selected congenital malformations: a nationwide case-control study.

@article{Kurppa1983CoffeeCD,
  title={Coffee consumption during pregnancy and selected congenital malformations: a nationwide case-control study.},
  author={Kari Kurppa and Petter Holmberg and Eeva Kuosma and Lauri Sax{\'e}n},
  journal={American journal of public health},
  year={1983},
  volume={73 12},
  pages={1397-9}
}
Finland leads the world in per capita coffee consumption. To evaluate the hypothesis that coffee consumption during pregnancy is teratogenic, 755 pairs of mothers of malformed children and their controls were personally interviewed soon after delivery. After excluding tea drinkers and pairs with inadequate information, the study group included 706 pairs. Study subjects consisted of mothers of children with 112 defects of the central nervous system, 241 orofacial clefts, 210 structural defects… CONTINUE READING

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