Coffee and the risk of hepatocellular carcinoma and chronic liver disease: a systematic review and meta-analysis of prospective studies

@article{Bravi2017CoffeeAT,
  title={Coffee and the risk of hepatocellular carcinoma and chronic liver disease: a systematic review and meta-analysis of prospective studies},
  author={Francesca Bravi and Alessandra Tavani and Cristina Bosetti and Paolo Boffetta and Carlo la Vecchia},
  journal={European Journal of Cancer Prevention},
  year={2017},
  volume={26},
  pages={368–377}
}
An inverse association has been reported between coffee drinking and the risk of hepatocellular carcinoma (HCC) and chronic liver disease (CLD), but its magnitude is still unclear. Thus, we carried out a systematic review and meta-analysis of prospective cohort studies that investigated the association between coffee consumption and the risk of HCC or CLD. We separately estimated the relative risk (RR) of the two conditions, for regular, low, and high consumption compared with no or occasional… 
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85 Citations
Highly Influential Citations
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85 Citations

Inverse Association of Coffee with Liver Cancer Development: An Updated Systematic Review and Meta-analysis.
TLDR
The authors' systematic review and meta-analysis suggests that drinking coffee provides benefits with a reduction in the risk of HCC or liver cancer and higher doses of coffee have higher benefits in terms of risk reduction.
Coffee Consumption and the Risk of Thyroid Cancer: A Systematic Review and Meta-Analysis
  • M. Han, Jin Hwa Kim
  • Medicine, Biology
    International journal of environmental research and public health
  • 2017
TLDR
There was no significant association between coffee consumption and thyroid cancer risk according to the meta-analysis results, and these findings should be interpreted with caution because of potential biases and confounding variables.
Coffee and cancer risk: a summary overview
TLDR
Overall, the overall evidence suggests no association of coffee intake with cancers of the stomach, pancreas, lung, breast, ovary, and prostate overall, and data are limited, with RR close to unity for other neoplasms.
Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose–response meta-analysis
TLDR
Increased consumption of caffeinated coffee and, to a lesser extent, decaffeinated coffee are associated with reduced risk of HCC, including in pre-existing liver disease.
An updated dose–response meta-analysis of coffee consumption and liver cancer risk
TLDR
A dose-response meta-analysis of prospective cohort studies of the association between coffee consumption and liver cancer risk suggested that coffee consumption is inversely associated with Liver cancer risk.
Coffee and the risk of hepatocellular carcinoma: misleading analysis of the data.
  • Xiao-yan Huang, Chao Hu
  • Medicine
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation
  • 2018
TLDR
There is one important methodological issue with the meta-analysis: pooling data extracted from inconsistent reference groups would significantly bias the summarized estimates aimed to quantify the relation between coffee consumption and the risk of HCC and would induce substantial heterogeneity.
Coffee Consumption and Risk of Biliary Tract Cancers and Liver Cancer: A Dose–Response Meta-Analysis of Prospective Cohort Studies
TLDR
It is suggested that increased coffee consumption is associated with decreased risk of liver cancer, but not BTC, and there was evidence of inverse correlation between coffee consumption and liver cancer risk.
Caffeinated Coffee Consumption and Health Outcomes in the US Population: A Dose-Response Meta-Analysis and Estimation of Disease Cases and Deaths Avoided.
TLDR
A meta-analysis of prospective studies investigating the magnitude and the dose-response shape of the associations between caffeinated coffee consumption and incidence/mortality of cardiovascular disease (CVD), as well as incidence of type 2 diabetes (T2D), hepatocellular carcinoma (HCC), endometrial cancer, melanoma, and nonmelanoma skin cancer confirms the beneficial health effects of coffee consumption in the US population, and quantifies their possible magnitude.
Coffee, green tea and liver cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population.
TLDR
Coffee drinking 'probably' decreases the risk of primary liver cancer among the Japanese population whereas the evidence on an association between green tea and liver cancer is 'insufficient' in this population.
Coffee consumption by type and risk of digestive cancer: a large prospective cohort study
TLDR
Evidence is found that coffee consumption was inversely associated with hepatocellular carcinoma which was similar by coffee type, and there were no significant consistently reduced risks of other individual digestive cancers amongst coffee drinkers.
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References

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TLDR
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