Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine.

@article{Johnston2003CoffeeAM,
  title={Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine.},
  author={Kelly L Johnston and Michael N Clifford and Linda Morgan},
  journal={The American journal of clinical nutrition},
  year={2003},
  volume={78 4},
  pages={
          728-33
        }
}
BACKGROUND Accumulating evidence suggests that certain dietary polyphenols have biological effects in the small intestine that alter the pattern of glucose uptake. Their effects, however, on glucose tolerance in humans are unknown. OBJECTIVE The objective was to investigate whether chlorogenic acids in coffee modulate glucose uptake and gastrointestinal hormone and insulin secretion in humans. DESIGN In a 3-way, randomized, crossover study, 9 healthy fasted volunteers consumed 25 g glucose… CONTINUE READING

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