Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials.

@article{Clark2017CoffeeCA,
  title={Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials.},
  author={Ian Clark and Hans-Peter Landolt},
  journal={Sleep medicine reviews},
  year={2017},
  volume={31},
  pages={
          70-78
        }
}
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212 Citations
Highly Influential Citations
7
Background Citations
70
Methods Citations
2
Results Citations
5

212 Citations

Citation Type

Citation Type

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The data suggest that abstaining from caffeine may not result in long‐term sleep improvement for habitual caffeine users, which contradicts the common sleep health recommendation.
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TLDR
It is concluded that a self‐regulating mechanism is likely to play a role, suggesting that students who know that caffeine negatively affects their sleep quality do not drink it in the evening, and that Caffeine sensitivity and the speed of caffeine metabolism may be confounding variables in this study.
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Distinct sensitivity to caffeine-induced insomnia related to age
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The results show an age-associated increase in caffeine- induced insomnia and poorer mental health indicators among people with caffeine-induced insomnia complaints.
The impact of daily caffeine intake on nighttime sleep in young adult men
TLDR
Investigating the sleep of twenty male young habitual caffeine consumers during a double-blind, randomized, crossover study indicates that daily caffeine intake in the morning and afternoon hours does not strongly impair nighttime sleep structure nor subjective sleep quality in healthy good sleepers who regularly consume caffeine.
Wide awake at bedtime? The effects of caffeine on sleep and circadian timing in teenagers - a randomized crossover trial
TLDR
In teenagers, evening caffeine intake of already 80 mg (i.e. ∼8fl oz of common energy drinks) is sufficient to promote alertness at the costs of subsequent sleep, consequently hampering the balanced interplay of sleep-wake regulatory components.
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Effects of chronic caffeine consumption on sleep and the sleep electroencephalogram in mice
TLDR
Chronic caffeine intake seems to increase the daily sleep–wake cycle amplitude and increase sleep pressure in mice, in contrast to the traditional conception on the impact on sleep.
Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives.
TLDR
This review discusses the current state of the science in model organisms and humans on the working mechanisms of adenosine and caffeine on sleep, and critically investigates the evidence for a direct involvement in sleep homeostatic mechanisms and whether the effects of caffeine onSleep differ between acute intake and chronic consumption.
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References

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Caffeine use as a model of acute and chronic insomnia.
TLDR
The data indicated that caffeine was effective in producing significant metabolic and sleep effects and that those effects were related, consistent with the interpretation that a chronic decrease in sleep efficiency associated with increased physiological arousal, although producing subjective dysphoria, does not produce a physiological sleep debt.
Effects of Caffeine are more Marked on Daytime Recovery Sleep than on Nocturnal Sleep
TLDR
It is proposed that the reduction of SWS by caffeine during daytime sleep increases the impact of the circadian wake signal on sleep, and has implications for individuals using caffeine during night time.
Acute and Chronic Effects of Caffeine on Performance, Mood, Headache, and Sleep
TLDR
Performance was found to be significantly impaired when caffeine was withdrawn abruptly following habitual use, and caffeine withdrawal was associated with reported increasses in frequency and severity of headache, and with reports of sleeping longer and more soundly.
Challenging sleep in aging: the effects of 200 mg of caffeine during the evening in young and middle‐aged moderate caffeine consumers
TLDR
Caffeine produced similar effects in young and middle‐aged subjects and sleep EEG results do not entirely support the hypothesis that caffeine fully mimics the effects of a reduction of homeostatic sleep propensity when following a normal sleep–wake cycle.
Effects of caffeine on daytime recovery sleep: A double challenge to the sleep-wake cycle in aging.
Pharmacokinetic and pharmacodynamic responses to caffeine in poor and normal sleepers
TLDR
The poor sleepers had significantly higher scores for neuroticism on the Eysenck Personality Questionnaire (EPQ) and anxiety on the Hospital Anxiety Depression (HAD) scale, compared with normal sleepers.
Caffeine eliminates psychomotor vigilance deficits from sleep inertia.
TLDR
Caffeine was efficacious in overcoming sleep inertia, which suggests a reason for the popularity of caffeine-containing beverages after awakening.
Caffeine intake (200 mg) in the morning affects human sleep and EEG power spectra at night
A naturalistic investigation of the effects of day-long consumption of tea, coffee and water on alertness, sleep onset and sleep quality
TLDR
It is demonstrated that day-long tea consumption produces similar alerting effects to coffee, despite lower caffeine levels, but is less likely to disrupt sleep, and ingestion of caffeinated beverages may maintain aspects of cognitive and psychomotor performance throughout the day and evening.
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