Cofactor engineering through heterologous expression of an NADH oxidase and its impact on metabolic flux redistribution in Klebsiella pneumoniae

Abstract

UNLABELLED BACKGROUND Acetoin is an important bio-based platform chemical. However, it is usually existed as a minor byproduct of 2,3-butanediol fermentation in bacteria. RESULTS The present study reports introducing an exogenous NAD+ regeneration sysytem into a 2,3-butanediol producing strain Klebsiella pneumoniae to increse the accumulation of… (More)
DOI: 10.1186/1754-6834-6-7

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@inproceedings{Ji2013CofactorET, title={Cofactor engineering through heterologous expression of an NADH oxidase and its impact on metabolic flux redistribution in Klebsiella pneumoniae}, author={Xiao-Jun Ji and Zhi-Fang Xia and Ning-Hua Fu and Zhi-Kui Nie and Meng-Qiu Shen and Qian-Qian Tian and He Huang}, booktitle={Biotechnology for biofuels}, year={2013} }