Cofactor dependence in furan reduction by Saccharomyces cerevisiae in fermentation of acid-hydrolyzed lignocellulose.

@article{Nilsson2005CofactorDI,
  title={Cofactor dependence in furan reduction by Saccharomyces cerevisiae in fermentation of acid-hydrolyzed lignocellulose.},
  author={Anneli Nilsson and Marie F. Gorwa-Grauslund and B{\"a}rbel Hahn-H{\"a}gerdal and G. Liden},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 12},
  pages={7866-71}
}
A decreased fermentation rate due to inhibition is a significant problem for economic conversion of acid-pretreated lignocellulose hydrolysates to ethanol, since the inhibition gives rise to a requirement for separate detoxification steps. Together with acetic acid, the sugar degradation products furfural and 5-hydroxymethyl furfural are the inhibiting compounds found at the highest concentrations in hydrolysates. These aldehydes have been shown to affect both the specific growth rate and the… CONTINUE READING
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