Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer.

@article{Krhn2001CoexpressionPO,
  title={Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer.},
  author={Gertraud M Kr{\"a}hn and Ulrike Leiter and Peter Kaskel and Martin Udart and Jochen Utikal and Guntram Bezold and Ralf U. Peter},
  journal={European journal of cancer},
  year={2001},
  volume={37 2},
  pages={251-9}
}
The receptor tyrosine kinases (RTKs) epidermal growth factor receptor (EGFR), HER2, HER3 and HER4 are involved in the pathogenesis of multiple human malignant neoplasias. However, their role in the carcinogenesis of basal cell carcinomas (BCC) and squamous cell carcinomas (SCC) remains to be elucidated. In order to further define the role of these RTKs, 56 human skin tissue samples of normal skin, BCC and SCC were studied by conventional and differential and quantitative reverse transcriptase… CONTINUE READING