Coexpression of preprotachykinin A and B transcripts in the bovine corpus luteum and evidence for functional neurokinin receptor activity in luteal endothelial cells and ovarian macrophages.

@article{Brylla2005CoexpressionOP,
  title={Coexpression of preprotachykinin A and B transcripts in the bovine corpus luteum and evidence for functional neurokinin receptor activity in luteal endothelial cells and ovarian macrophages.},
  author={Elke Brylla and Gabriela Aust and Maren Geyer and Ortrud Uckermann and Sabine Loeffler and Katherina Spanel-Borowski},
  journal={Regulatory peptides},
  year={2005},
  volume={125 1-3},
  pages={125-33}
}
Nonneuronal cell sources of tachykinins, such as substance P (SP) and neurokinin B (NKB), have been demonstrated in leukocytes, endothelial cells and endocrine cells, and may play a role in corpus luteum (CL) development. For this reason, we analyzed mRNA presence for the two tachykinin precursors together with the neurokinin-1 receptor and the neurokinin-3 receptor (NK-1R and NK-3R, preferred by SP and NKB, respectively) in bovine CL at various stages in the luteal phase. Using the RT-PCR… CONTINUE READING
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