Coexpression of NUP98/TOP1 and TOP1/NUP98 in de novo Acute Myeloid Leukemia with t(11;20)(p15;q12) and t(2;5)(q33;q31).

Abstract

The t(11;20)(p15;q11∼12) translocation is a very rare but recurrent cytogenetic aberration that occurs in myelodysplastic syndrome/acute myeloid leukemia (MDS/AML). This translocation was shown to form a fusion gene between NUP98 at 11p15 and TOP1 at 20q12. Here, we describe a new case of de novo AML M2 with t(11;20) which was associated with another… (More)
DOI: 10.1159/000458168

Topics

Cite this paper

@article{Yamamoto2016CoexpressionON, title={Coexpression of NUP98/TOP1 and TOP1/NUP98 in de novo Acute Myeloid Leukemia with t(11;20)(p15;q12) and t(2;5)(q33;q31).}, author={Katsuya Yamamoto and Yosuke Minami and Kimikazu Yakushijin and Y. Mizutani and Yumiko Inui and Shinichiro Kawamoto and Keiji Matsui and Yuji Nakamachi and Seiji Kawano and Hiroshi Matsuoka and Hironobu Minami}, journal={Cytogenetic and genome research}, year={2016}, volume={150 3-4}, pages={287-292} }