Coexpression of MUC1 mucin peptide core and the Thomsen-Friedenreich antigen in colorectal neoplasms.

@article{Baldus1998CoexpressionOM,
  title={Coexpression of MUC1 mucin peptide core and the Thomsen-Friedenreich antigen in colorectal neoplasms.},
  author={Stephan Ernst Baldus and Franz-Georg Hanisch and G M Kotlarek and Thomas K. Zirbes and Juergen Thiele and Johannes Zander Tobias Isenberg and Uwe Karsten and Peter L. Devine and Hans Peter Dienes},
  journal={Cancer},
  year={1998},
  volume={82 6},
  pages={1019-27}
}
BACKGROUND Controversial findings have been reported regarding the expression of the Thomsen-Friedenreich (TF) antigen in colorectal neoplasms when different monoclonal antibodies (MoAbs) have been used. Moreover, there is no information available regarding the carrier protein(s) of this antigen. METHODS Forty-five colorectal adenomas and 48 carcinomas were studied by avidin-biotin complex-peroxidase immunohistochemistry. The immunohistochemistry employed the MoAb BW835, which was reactive to… CONTINUE READING

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