Coexistent Linear Scleroderma and Juvenile Systemic Lupus Erythematosus

  title={Coexistent Linear Scleroderma and Juvenile Systemic Lupus Erythematosus},
  author={M. Majeed and Sulaiman M. Al‐Mayouf and Essam Al-Sabban and Sultan A. Bahabri},
  journal={Pediatric Dermatology},
Abstract: We describe a girl who initially presented with linear scleroderma. Five and a half years later she developed systemic lupus erythematosus (SLE). Previous descriptions of the coexistence of linear scleroderma and SLE in childhood are reviewed. 
Systemic manifestations in localized scleroderma
  • F. Zulian
  • Medicine
    Current rheumatology reports
  • 2004
In this paper, the various systemic manifestations reported in localized scleroderma, their incidence, their relationship with systemic sclerosis, and their relationship with other autoimmune or
Multifocal lesions of morphoea in a patient with systemic lupus erythematosus
A 23‐year‐old man presented with multiple, brownish, sclerotic patches on his forehead and temple, which had first appeared 1 month previously, and Histopathological examination showed a pattern consistent with morphoea.
A rare association of localized scleroderma type morphea, vitiligo, autoimmune hypothyroidism, pneumonitis, autoimmune thrombocytopenic purpura and central nervous system vasculitis. Case report
It is likely that LS have an autoimmune origin and in this case becomes part of MAS, which consist on the presence of three or more well-defined autoimmune diseases in a single patient.
Case Report: Morphea Profunda Associated with Helicobacter pylori Infection in Sudanese Patient
The cases were diagnosed and confirmed histopathologically as Morphea profunda, considered to be the first two cases of HSD been reported in Sudan.
Scleroderma overlap syndromes.
  • J. Pope
  • Medicine, Biology
    Current opinion in rheumatology
  • 2002
This article will review recent literature to help in the understanding of scleroderma with overlap features and suggest distinct features of diffuse sclerodma with positive Scl-70, pulmonary fibrosis, and later seropositive erosive rheumatoid arthritis.
Distinct autoimmune syndromes in morphea: a review of 245 adult and pediatric cases.
High prevalences of concomitant and familial autoimmune disease, systemic manifestations, and antinuclear antibody positivity in the generalized and possibly mixed subtypes suggest that these are systemic autoimmune syndromes and not skin-only phenomena.
High frequency of genital lichen sclerosus in a prospective series of 76 patients with morphea: toward a better understanding of the spectrum of morphea.
Genital LS is significantly more frequent in patients with morphea than in unaffected individuals and thus needs treatment with topical corticosteroids, and complete clinical examination should therefore be mandatory in patientsWith morphea because genital LS bears a risk of evolution into squamous cell carcinoma.
Concurrent Parry-Romberg Syndrome and Systemic Lupus Erythematosus
A Parry-Romberg syndrome patient with positive ANA and presence of anti-double- stranded DNA antibodies who then developed systemic lupus erythematosus is reported, carrying the risk of developing systemic collagen-vascular disorders.
Morphea and antithyroid antibodies
Although morphea is an autoimmune disease, it does not seem to be associated with increased prevalence of positive antithyroid antibodies, and there is no need to perform routine laboratory tests for thyroid disorders in patients with morphea.
Parry-Romberg Concurrent Parry-Romberg Syndrome and Systemic Lupus Erythematosus
A Parry-Romberg syndrome patient with positive ANA and presence of anti-doublestranded DNA antibodies who then developed systemic lupus erythematosus is reported, carrying the risk of developing systemic collagen-vascular disorders.


Linear scleroderma occurring in a patient with systemic lupus erythematosus--short report.
A 38-year-old woman with systemic lupus erythematosus had developed a cutaneous lesion of linear scleroderma on the forehead 4 years after the diagnosis of lupus erythematosus. This case of
Linear scleroderma, hemiatrophy and systemic lupus erythematosus.
A young woman, with linear scleroderma accompanied by body hemiatrophy since childhood, developed systemic lupus erythematosus. The rare coexistence of the 2 diseases is discussed.
Concurrent linear scleroderma and systemic lupus erythematosus: a report of two cases.
Two patients with linear scleroderma developed systemic lupus erythematosus (SLE) and development of more serious clinical involvement and antibodies to Sm or native deoxyribonucleic acid (nDNA) helped establish a diagnosis of SLE.
Generalized morphea and idiopathic thrombocytopenia.
Concurrent localized scleroderma and discoid lupus erythematosus. Cutaneous 'mixed' or 'overlap' syndrome.
Four patients with concurrent, chronic, progessive, localized scleroderma and discoid lupus erythematosus were studied and rare cutaneous disease similar to systemic, "mixed," or "overlap" connective tissue disease exists and offers an opportunity to study unusual immunologic and pathological events in both sclerodma and LE.
Circumscribed scleroderma with immunologic evidence of systemic lupus erythematosus.
An 8-year-old girl initially manifested clinical and histopathologic findings of circumscribed scleroderma, but laboratory evaluation revealed substantial evidence of systemic lupus erythematosus (SLE).
Juvenile linear scleroderma associated with serologic abnormalities.
Patients with linear scleroderma may be at some risk for developing systemic collagen-vascular diseases and should give a complete history and receive a thorough physical examination as well as undergo laboratory evaluations for the presence of ANA and rheumatoid factor.
Scleroderma in childhood.
Concurrent multiple morphea and neonatal lupus erythematosus in an infant boy born to a mother with SLE
An infant boy born to a mother with systemic lupus ery thematosus developed multiple morphea and annular erythematous lesions and Histological findings in the sclerotic lesions were consistent with scleroderma.
Linear scleroderma. Clinical spectrum, prognosis, and laboratory abnormalities.
The clinical features and natural history of linear scleroderma in 53 patients and the laboratory tests helpful in the management of this disease are described. No patient had Raynaud's phenomenon or