Coexistence of systemic lupus erythematosus, tuberous sclerosis and aggressive natural killer-cell leukaemia: coincidence or correlated?

@article{Bekkink2016CoexistenceOS,
  title={Coexistence of systemic lupus erythematosus, tuberous sclerosis and aggressive natural killer-cell leukaemia: coincidence or correlated?},
  author={Marleen Olde Bekkink and Y M Ahmed-Ousenkova and Mihai G Netea and Walter JFM van der Velden and Jo H. M. Berden},
  journal={Lupus},
  year={2016},
  volume={25 7},
  pages={766-71}
}
Among patients with systemic lupus erythematosus (SLE) there is an increased risk of haematological malignancies, especially non-Hodgkin lymphoma. However, the association of SLE with aggressive CD3 negative natural killer (NK)-cell leukaemia has not been reported so far. We present a case of a 39-year-old woman with SLE, aggressive NK-cell leukaemia and tuberous sclerosis complex. The prior probability of developing the combination of these three rare diseases by coincidence is extremely low… CONTINUE READING
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