Coexistence of renin and cathepsin B in epithelioid cell secretory granules


Mature juxtaglomerular epithelioid cell secretory granules of the rat exhibit both renin- and cathepsin B-like immunoreactivity. On the basis of the coexistence with renin at a pH which, according to previous experiments, is probably in the range of that in lysosomes, cathepsin B is suggested to be involved in the activation of renin prior to secretion.

DOI: 10.1007/BF00495138

4 Figures and Tables


Citations per Year

5,689 Citations

Semantic Scholar estimates that this publication has 5,689 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Taugner1985CoexistenceOR, title={Coexistence of renin and cathepsin B in epithelioid cell secretory granules}, author={Roland Taugner and Ch. Ph. B{\"{u}hrle and Rainer Nobiling and Heidrun Kirschke}, journal={Histochemistry}, year={1985}, volume={83}, pages={103-108} }