Coexistence of renin and cathepsin B in epithelioid cell secretory granules

Abstract

Mature juxtaglomerular epithelioid cell secretory granules of the rat exhibit both renin- and cathepsin B-like immunoreactivity. On the basis of the coexistence with renin at a pH which, according to previous experiments, is probably in the range of that in lysosomes, cathepsin B is suggested to be involved in the activation of renin prior to secretion.

DOI: 10.1007/BF00495138

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@article{Taugner1985CoexistenceOR, title={Coexistence of renin and cathepsin B in epithelioid cell secretory granules}, author={Roland Taugner and Ch. Ph. B{\"{u}hrle and Rainer Nobiling and Heidrun Kirschke}, journal={Histochemistry}, year={1985}, volume={83}, pages={103-108} }