Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers.

@article{Busto2009CoexistenceOI,
  title={Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers.},
  author={Jon V. Busto and Mar{\'i}a L Fanani and L A Luis A de Tullio and Jes{\'u}s Sot and Bruno Maggio and F{\'e}lix M Go{\~n}i and Alicia Alonso},
  journal={Biophysical journal},
  year={2009},
  volume={97 10},
  pages={2717-26}
}
A combination of lipid monolayer- and bilayer-based model systems has been applied to explore in detail the interactions between and organization of palmitoylsphingomyelin (pSM) and the related lipid palmitoylceramide (pCer). Langmuir balance measurements of the binary mixture reveal favorable interactions between the lipid molecules. A thermodynamically stable point is observed in the range approximately 30-40 mol % pCer. The pSM monolayer undergoes hyperpolarization and condensation with… CONTINUE READING