Coenzymes as fossils of an earlier metabolic state

@article{White2005CoenzymesAF,
  title={Coenzymes as fossils of an earlier metabolic state},
  author={H. White},
  journal={Journal of Molecular Evolution},
  year={2005},
  volume={7},
  pages={101-104}
}
  • H. White
  • Published 2005
  • Biology, Medicine
  • Journal of Molecular Evolution
  • SummaryA metabolic system composed of nucleic acid enzymes is proposed to have existed prior to the evolution of ribosomal protein synthesis. Vestiges of these nucleic acid enzymes persist in contemporary coenzymes. This proposal rationalizes the fact that many coenzymes are nucleotides or heterocyclic bases which could be derived from nucleotides. 

    Topics from this paper.

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 10 REFERENCES
    Chemical and biological evolution of a nucleotide-binding protein
    • 1,289
    On earlier states of the biochemical system.
    • 173
    β structures of alternating polypeptides and their possible prebiotic significance
    • 201
    [Catalytic role for RNA in DNA replication].
    • 11
    • PDF
    A proposed model for interaction of polypeptides with RNA.
    • 122
    • PDF
    Selforganization of matter and the evolution of biological macromolecules
    • 2,968
    • PDF
    Making Conferences Successful
    • 24
    AN APPROACH TO THE EVOLUTION OF METABOLISM.
    • 29
    • PDF
    Self-organization of molecular systems and evolution of the genetic apparatus.
    • 93
    The evolution of dehydrogenases and kinases.
    • 61