Coenzymes as fossils of an earlier metabolic state

  title={Coenzymes as fossils of an earlier metabolic state},
  author={H. B. White},
  journal={Journal of Molecular Evolution},
  • H. B. White
  • Published 2005
  • Biology, Medicine
  • Journal of Molecular Evolution
SummaryA metabolic system composed of nucleic acid enzymes is proposed to have existed prior to the evolution of ribosomal protein synthesis. Vestiges of these nucleic acid enzymes persist in contemporary coenzymes. This proposal rationalizes the fact that many coenzymes are nucleotides or heterocyclic bases which could be derived from nucleotides. 
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