Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity.

@article{Conklin2005CoenzymeQF,
  title={Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity.},
  author={Kenneth A. Conklin},
  journal={Integrative cancer therapies},
  year={2005},
  volume={4 2},
  pages={110-30}
}
Preclinical and clinical studies suggest that anthracycline-induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin. Studies further suggest that coenzyme Q10 does not interfere with the antineoplastic action of anthracyclines and might even enhance their anticancer effects. Preventing cardiotoxicity might allow for escalation of the anthracycline dose, which would further enhance the anticancer… CONTINUE READING

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Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
Damage to mitochondrial DNA blocks the regenerative capability of the organelle and ultimately leads to apoptosis or necrosis of myocytes .
Damage to mitochondrial DNA blocks the regenerative capability of the organelle and ultimately leads to apoptosis or necrosis of myocytes .
Damage to mitochondrial DNA blocks the regenerative capability of the organelle and ultimately leads to apoptosis or necrosis of myocytes .
Damage to mitochondrial DNA blocks the regenerative capability of the organelle and ultimately leads to apoptosis or necrosis of myocytes .
Damage to mitochondrial DNA blocks the regenerative capability of the organelle and ultimately leads to apoptosis or necrosis of myocytes .
AnthracyclinesChemical structure ofDaunorubicin
Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
AnthracyclinesChemical structure ofDoxorubicin
Preclinical and clinical studies suggest that anthracycline - induced cardiotoxicity can be prevented by administering coenzyme Q10 during cancer chemotherapy that includes drugs such as doxorubicin and daunorubicin .
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