Coenzyme Q10 supplementation in the management of statin‐associated myalgia
@article{Tan2017CoenzymeQS, title={Coenzyme Q10 supplementation in the management of statin‐associated myalgia}, author={Jason Eng Thye Tan and Arden R. Barry}, journal={American Journal of Health-System Pharmacy}, year={2017}, volume={74}, pages={786,788,790–791,793} }
Statins are indicated for use as first-line therapy in the prevention of major adverse cardiovascular events (e.g., myocardial infarction, stroke) in patients with or at risk for cardiovascular disease.[1][1] However, muscle-related adverse effects, including myopathy, often limit the use of statins
5 Citations
Coenzyme Q10 for statin-associated myalgia.
- MedicineAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
- 2018
The authors omitted clinically relevant information and coenzyme Q10 supplementation in the management of statin-associated myalgia (SAM) and believe it plays a role in practice.
Do PCSK9 inhibitors reduce cardiovascular events?
- BiologyCanadian family physician Medecin de famille canadien
- 2018
For patients with CVD taking maximally tolerated statins, adding evolocumab or alirocumab decreases new CVD events for an additional 1 in 65 patients.
Prevention and management of statin adverse effects: A practical approach for pharmacists
- MedicineCanadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC
- 2018
A thorough assessment of patients’ clinical and laboratory history should be performed in any patient presenting with muscle symptoms on statin therapy, followed by a systematic dechallenge/rechallenge approach, ensuring patients are appropriately receiving a statin and aware of both the benefits and risks of therapy.
The Interplay between Oxidative Stress, Exercise, and Pain in Health and Disease: Potential Role of Autonomic Regulation and Epigenetic Mechanisms
- Biology, PsychologyAntioxidants
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The relation between oxidative stress, exercise, and pain is poorly understood and not straightforward, as it is dependent on the characteristics of exercise, but also on which population is investigated, and strict guidelines should be developed to limit the effect of several confounding factors.
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