Coenzyme Q10 prevents human lens epithelial cells from light-induced apoptotic cell death by reducing oxidative stress and stabilizing BAX / Bcl-2 ratio.

@article{Kernt2009CoenzymeQP,
  title={Coenzyme Q10 prevents human lens epithelial cells from light-induced apoptotic cell death by reducing oxidative stress and stabilizing BAX / Bcl-2 ratio.},
  author={Marcus Kernt and Christoph Hirnei{\ss} and Aljoscha Steffen Neubauer and Michael Werner Ulbig and Anselm Kampik},
  journal={Acta ophthalmologica},
  year={2009},
  volume={88 3},
  pages={
          e78-86
        }
}
BACKGROUND Cataract is one of the most prevalent eye disease and a major cause for legal blindness in the world. Beside others, cumulative light-exposure and apoptotic cell death are significantly associated with cataract development. In contrast, supplementation with antioxidants has been suggested to prevent premature cataractogenesis. This study investigates possible protective effects of Coenzyme Q10 (CoQ10) regarding light-induced stress and apoptotic cell death in human lens epithelial… CONTINUE READING
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