Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth1

@inproceedings{TarryAdkins2016CoenzymeQP,
  title={Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth1},
  author={Jane L Tarry-Adkins and Denise S Fernandez-Twinn and Iain P. Hargreaves and Viruna Neergheen and Catherine E M Aiken and Malgorzata S. Martin-Gronert and Josie M L McConnell and Susan E Ozanne},
  booktitle={The American journal of clinical nutrition},
  year={2016}
}
BACKGROUND It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmental programming are not well characterized, and potential intervention strategies are poorly defined. OBJECTIVES We tested the hypotheses that poor maternal nutrition and accelerated postnatal growth would lead to increased hepatic fibrosis (a pathological marker of liver dysfunction) and that… CONTINUE READING
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