Coenzyme Q10 oral bioavailability: effect of formulation type

  title={Coenzyme Q10 oral bioavailability: effect of formulation type},
  author={A. Barakat and R. Shegokar and M. Dittgen and R. M{\"u}ller},
  journal={Journal of Pharmaceutical Investigation},
  • A. Barakat, R. Shegokar, +1 author R. Müller
  • Published 2013
  • Chemistry
  • Journal of Pharmaceutical Investigation
  • Abstract Coenzyme Q10 (Q10) has a poor bioavailability due to its very low aqueous solubility and high molecular weight. The purpose of this review is to discuss the different types of Q10 drug delivery systems (DDS) ranging from the simple oily dispersions to the nanotechnology-oriented systems such as nanocrystals, self-nanoemulsified drug delivery systems, etc. to overcome the solubility issue. The basics of these approaches were discussed in relationship to the effect of Q10 absorption. For… CONTINUE READING
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