Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue.

@article{Rosenfeldt1999CoenzymeQI,
  title={Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue.},
  author={Franklin Rosenfeldt and Salvatore Pepe and Ruchong Ou and Justin A. Mariani and Michael Anthony Rowland and Phillip Nagley and Anthony William Linnane},
  journal={BioFactors},
  year={1999},
  volume={9 2-4},
  pages={
          291-9
        }
}
The inferior recovery of cardiac function after interventional cardiac procedures in elderly patients compared to younger patients suggests that the aged myocardium is more sensitive to stress. We report two studies that demonstrate an age-related deficit in myocardial performance after aerobic and ischemic stress and the capacity of CoQ10 treatment to correct age-specific diminished recovery of function. In Study 1 the functional recovery of young (4 mo) and senescent (35 mo) isolated working… CONTINUE READING
BETA