• DOI:10.1161/CIRCHEARTFAILURE.115.002639
Corpus ID: 2034503

Coenzyme Q10 and Heart Failure: A State-of-the-Art Review

@article{Sharma2016CoenzymeQA,
  title={Coenzyme Q10 and Heart Failure: A State-of-the-Art Review},
  author={Abhinav Sharma and G. Fonarow and J. Butler and J. Ezekowitz and G. M. Felker},
  journal={Circulation: Heart Failure},
  year={2016},
  volume={9},
  pages={e002639}
}

Abhinav Sharma, G. Fonarow, +2 authors G. M. Felker

Published 2016

Medicine

Circulation: Heart Failure

Heart failure (HF) with either preserved or reduced ejection fraction is associated with increased morbidity and mortality. Evidence-based therapies are often limited by tolerability, hypotension, electrolyte disturbances, and renal dysfunction. Coenzyme Q10 (CoQ10) may represent a safe therapeutic option for patients with HF. CoQ10 is a highly lipophilic molecule with a chemical structure similar to vitamin K. Although being a common component of cellular membranes, CoQ10’s most prominent role… CONTINUE READING

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