Coenzyme Q10 and Heart Failure: A State-of-the-Art Review

  title={Coenzyme Q10 and Heart Failure: A State-of-the-Art Review},
  author={Abhinav Sharma and G. Fonarow and J. Butler and J. Ezekowitz and G. M. Felker},
  journal={Circulation: Heart Failure},
  • Abhinav Sharma, G. Fonarow, +2 authors G. M. Felker
  • Published 2016
  • Medicine
  • Circulation: Heart Failure
  • Heart failure (HF) with either preserved or reduced ejection fraction is associated with increased morbidity and mortality. Evidence-based therapies are often limited by tolerability, hypotension, electrolyte disturbances, and renal dysfunction. Coenzyme Q10 (CoQ10) may represent a safe therapeutic option for patients with HF. CoQ10 is a highly lipophilic molecule with a chemical structure similar to vitamin K. Although being a common component of cellular membranes, CoQ10’s most prominent role… CONTINUE READING
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