Coenzyme Q10 and Heart Failure: A State-of-the-Art Review
@article{Sharma2016CoenzymeQA, title={Coenzyme Q10 and Heart Failure: A State-of-the-Art Review}, author={Abhinav Sharma and G. Fonarow and Javed Butler and Justin A. Ezekowitz and G. Michael Felker}, journal={Circulation: Heart Failure}, year={2016}, volume={9}, pages={e002639} }
Heart failure (HF) with either preserved or reduced ejection fraction is associated with increased morbidity and mortality. Evidence-based therapies are often limited by tolerability, hypotension, electrolyte disturbances, and renal dysfunction. Coenzyme Q10 (CoQ10) may represent a safe therapeutic option for patients with HF. CoQ10 is a highly lipophilic molecule with a chemical structure similar to vitamin K. Although being a common component of cellular membranes, CoQ10’s most prominent role…
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