Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics

  title={Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics},
  author={H. Bhagavan and R. K. Chopra},
  journal={Free Radical Research},
  pages={445 - 453}
  • H. Bhagavan, R. K. Chopra
  • Published 2006
  • Chemistry, Medicine
  • Free Radical Research
  • Available data on the absorption, metabolism and pharmacokinetics of coenzyme Q10 (CoQ10) are reviewed in this paper. [...] Key Result The T(max) is around 6 h, with an elimination half-life of about 33 h. The reference intervals for plasma CoQ10 range from 0.40 to 1.91 micromol/l in healthy adults. With CoQ10 supplements there is reasonable correlation between increase in plasma CoQ10 and ingested dose up to a certain point. Animal data show that CoQ10 in large doses is taken up by all tissues including heart…Expand Abstract
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