• Corpus ID: 43938558

Coenzyme Q 10 in cardiovascular disease

  title={Coenzyme Q 10 in cardiovascular disease},
  author={Salvatore Pepe and Silvana F. Marasco and Steven Joseph Haas and Freya L. Sheeran and Henry Krum and Franklin Rosenfeldt},
In this review we summarise the current state of knowledge of the therapeutic efficacy and mechanisms of action of CoQ10 in cardiovascular disease. Our conclusions are: 1. There is promising evidence of a beneficial effect of CoQ10 when given alone or in addition to standard therapies in hypertension and in heart failure, but less extensive evidence in ischemic heart disease. 2. Large scale multi-centre prospective randomised trials are indicated in all these areas but there are difficulties in… 

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