• Corpus ID: 14506815

Coenzyme Q 10 and Its Role in Cardiomyopathy and Heart Failure in Adults

  title={Coenzyme Q 10 and Its Role in Cardiomyopathy and Heart Failure in Adults},
  author={Uma Singh and Sridevi Devaraj and Ishwarlal Jialal},
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the Western world. Oxidative stress appears to play a pivotal role in atherosclerosis. Coenzyme Q10 (CoQ10), one of the most important antioxidants, is synthesized de novo by every cell in the body. Its biosynthesis decreases with age and its deficit in tissues is associated with degenerative changes of aging, thus implicating a possible therapeutic role of CoQ10 in human diseases. There is evidence to support the… 

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