Coenzyme A: to make it or uptake it?

@article{Sibon2016CoenzymeAT,
  title={Coenzyme A: to make it or uptake it?},
  author={O. Sibon and E. Strauss},
  journal={Nature Reviews Molecular Cell Biology},
  year={2016},
  volume={17},
  pages={605-606}
}
The consensus has been that intracellular coenzyme A (CoA) is obtained exclusively by de novo biosynthesis via a universal, conserved five-step pathway in the cell cytosol. However, old and new evidence suggest that cells (and some microorganisms) have several strategies to obtain CoA, with 4′-phosphopantetheine (P-PantSH; the fourth intermediate in the canonical CoA biosynthetic pathway) serving as a 'nexus' metabolite. 
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