Coeliac disease and malignancies

@article{Ferguson1996CoeliacDA,
  title={Coeliac disease and malignancies},
  author={Anne Ferguson and Kathleen Kingstone},
  journal={Acta P{\ae}diatrica},
  year={1996},
  volume={85}
}
When compared with the general population, patients with coeliac disease (CD) have an increased risk of developing enteropathy‐associated T‐cell lymphoma (EATCL), esophageal and pharyngeal squamous carcinomas and small intestinal adenocarcinomas. The prevalence of histologically confirmed CD in Edinburgh and the Lothians in 1979 was 61 per 100000. The National Health Service Central Records of all 653 subjects registered at that time have been flagged, allowing us to analyse mortality in CD. At… 
Coeliac disease and malignancy.
  • G. Holmes
  • Medicine
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2002
TLDR
Case-finding rather than blanket population screening is to be recommended on present evidence, and research into the role of intraepithelial lymphocytes in the genesis of lymphoma has indicated that non-responsive coeliac disease and ulcerative jejunoileitis are part of the lymphoma spectrum.
Intestinal B Cell Lymphoma Associated with Chronic Hepatitis C and Celiac Disease
TLDR
The following is a case report of a patient with CD and hepatitis C who developed intestinal diffuse large B cell lymphoma, a rare complication of CD, and the possible mechanisms in the light of the pertinent literature.
Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis.
TLDR
The relative risks for lymphomas and gastrointestinal cancers in this study are lower (and declining) than in most previous reports, and the overall cancer risk is only moderately increased, and nonelevated during childhood and adolescence.
Celiac Disease and Lymphoma Risk: A Multicentric Case–Control Study in Spain
TLDR
There was no evidence that celiac disease was a risk factor for lymphoma, and serological screening for CD is not recommended in people with lymphoma.
Malignancy in Coeliac Disease and Dermatitis Herpetiformis
TLDR
Treatment of the predisposing condition decreases the risk of developing subsequent malignancy, and various studies to a higher incidence of non-Hodgkin's lymphoma in celiac patients than in general population.
Celiac disease and esophageal cancer.
Background:  Northeastern Iran has a high incidence for squamous cell esophageal carcinoma (ESCC). The aim of the study is to the assess relationship between celiac disease (CD) and ESCC. Materials
A prospective study of the incidence of childhood celiac disease.
TLDR
C celiac disease may affect 0.9% of Denver children by 5 years of age, and children positive for the HLA-DR3 allele and females appear to be at increased risk.
Factors associated with carcinoma of the oesophagus at Mulago Hospital, Uganda.
TLDR
Many patients referred for EGD in Uganda had esophageal cancer most of which were smoking, male gender and older age were risk factors, and Preventive measures should target stopping smoking.
Gastrointestinal lymphoma: prevention and treatment of early lesions.
TLDR
The pathogenic role of Helicobacter pylori and gluten has been demonstrated in gastric lymphoma and enteropathy-associated T-cell lymphoma respectively, while environmental factors may play a major role in the pathogenesis of alpha-chain disease.
Cancer incidence in a population‐based cohort of patients with Wegener's granulomatosis
TLDR
Assessing the general incidence of cancer in patients with Wegener's granulomatosis confirmed previous indications of an increased risk for cancer of the urinary bladder but also points to increased risks for cancer at other sites.
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TLDR
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TLDR
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TLDR
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TLDR
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CASE 1 A man aged 50 years was in good health until April 1961, when he complained of pain in the right buttock and was treated with phenylbutazone. He afterwards developed watery diarrhoea, passing
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TLDR
'coeliac disease' needs to be replaced by a more generally inclusive and flexible term such as 'gluten sensitivity', defined as a state ofT cell sensitisation to gluten in a genetically predisposed subject.
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TLDR
Lymphoma complicating coeliac disease appears to be of T-cell, rather than histiocyte, origin.
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TLDR
The celiaclike intestinal antibody pattern and a high IEL count may be markers of latent gluten-sensitive enteropathy; some of these patients are clinically gluten sensitive in the absence of enteropathy.
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