Coeliac disease and autoimmune disease—genetic overlap and screening

  title={Coeliac disease and autoimmune disease—genetic overlap and screening},
  author={Knut E. A. Lundin and Cisca Wijmenga},
  journal={Nature Reviews Gastroenterology \&Hepatology},
  • K. Lundin, C. Wijmenga
  • Published 1 September 2015
  • Medicine, Biology
  • Nature Reviews Gastroenterology &Hepatology
Coeliac disease is a treatable, gluten-induced disease that often occurs concurrently with other autoimmune diseases. In genetic studies since 2007, a partial genetic overlap between these diseases has been revealed and further insights into the pathophysiology of coeliac disease and autoimmunity have been gained. However, genetic screening is not sensitive and specific enough to accurately predict disease development. The current method to diagnose individuals with coeliac disease is… 
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