Coeliac disease

  title={Coeliac disease},
  author={Antonio di Sabatino and Gino Roberto Corazza},
  journal={The Lancet},
Coeliac disease is a chronic inflammatory disorder of the small bowel induced in genetically susceptible people by the irritant gluten and possibly other environmental cofactors. The disorder is characterised by a diverse clinical heterogeneity that ranges from asymptomatic to severely symptomatic, and it manifests with frank malabsorption, an increased morbidity attributable to the frequent association with autoimmune disorders and increased mortality resulting from the emergence of T-cell… Expand
Glossodynia and coeliac disease
A 72-year-old woman with a four months history of oral burning sensation is reported on, highlighting the importance of considering coeliac disease in managing cases of idiopathic glossodynia. Expand
The Possible Role of Pathogenic and non-Pathogenic Bacteria in Initiation and Exacerbation of Celiac Disease.
The current review-based study aims to discuss the possible relationship between CD and pathogenic and non-pathogenic bacteria and to show various and significant aspects of mechanisms involved in the CD process. Expand
Functional and metabolic disorders in celiac disease: new implications for nutritional treatment.
This review focuses on the principal functional and metabolic disorders in both treated and untreated CD, ranging from alterations of the gastrointestinal system to impaired glucose and lipid metabolism and insulin secretion with the aim of providing new implications beyond a GFD, for an ad hoc nutrition treatment in patients. Expand
Non-celiac gluten sensitivity. Is it in the gluten or the grain?
The current knowledge on non-celiac gluten sensitivity is reviewed, and potential pathogenic pathways of different gluten related disorders are outlined in order to gain clues about the pathophysiology of this novel condition. Expand
Dermatitis Herpetiformis: A Cutaneous Gluten-Related Disorder with Possible Exception in Asian Patients
This review focuses on the confirmed features of DH and the recent findings specific to DH in Japanese patients. Expand
Serology in adults with celiac disease: limited accuracy in patients with mild histological lesions
The severity of mucosal damage is the main factor governing the detectability of serological markers of CD and the sensitivity of serology testing is questionable in patients with minimal lesions. Expand
Are stem cells a potential therapeutic tool in coeliac disease?
The lack of immunogenicity makes mesenchymal stem cells more suitable than their haematopoietic counterpart, since their transplantation may be performed in the absence of a myeloablative conditioning regimen. Expand
[Non-celiac Gluten Sensitivity].
New evidence shows that a gluten-free diet may be beneficial for some patients with gastrointestinal symptoms, such as those symptoms commonly found in patients with IBS. Expand
Celiac crisis and hemorrhagic diathesis in an adult
C celiac disease usually manifests itself through chronic diarrhea, abdominal pain and weight loss, but celiac crisis and hemorrhagic diathesis, although rarely, may also occur. Expand
Hematemesis as an Initial Presentation of Enteropathy-Associated T-Cell Lymphoma
A unique case of EATL who presented with acute and severe gastrointestinal bleeding with no prior history of CD is presented. Expand