Coeliac disease

@article{Green2003CoeliacD,
  title={Coeliac disease},
  author={PeterJ. Green and Bana Jabri},
  journal={The Lancet},
  year={2003},
  volume={362},
  pages={383-391}
}
Coeliac disease is a genetically-determined chronic inflammatory intestinal disease induced by an environmental precipitant, gluten. Patients with the disease might have mainly non-gastrointestinal symptoms, and as a result patients present to various medical practitioners. Epidemiological studies have shown that coeliac disease is very common and affects about one in 250 people. The disease is associated with an increased rate of osteoporosis, infertility, autoimmune diseases, and malignant… Expand

Paper Mentions

Observational Clinical Trial
Being diagnosed with coeliac disease means that individuals can no longer consume things containing gluten, such as bread or cake, or they can become very ill. This can make… Expand
ConditionsCeliac, Celiac Disease, Celiac Disease in Children, (+4 more)
InterventionOther
[An update on the pathogenesis of celiac disease].
TLDR
This is the only autoimmune disease whose precipitating factor for immunological tissue damage is known and it is clear that genetic, environmental and immunological factors play a role. Expand
Celiac Disease: Complications and the role of Infection in Pathogenesis
TLDR
CD is modestly associated with future venous thromboembolism (VTE), end-stage renal disease (ESRD), and IgA nephropathy (IgAN) in individuals with CD, and the pathogenesis of CD is further investigated by assessing the effect of infectious disease at time of gluten introduction in infants on the risk of future CD. Expand
Management of celiac disease in daily clinical practice.
TLDR
Although CD is a well-characterized disease, it is grossly underdiagnosed, despite the severe consequences of long-term gluten ingestion in CD, such as enhanced autoimmunity, refractory CD and intestinal T cell lymphoma. Expand
Celiac disease: from pathogenesis to novel therapies.
TLDR
Based on the advanced understanding of the pathogenesis of celiac disease, targeted nondietary therapies have been devised, and some are already in phase 1 or 2 clinical trials. Expand
Safety Food in Celiac Disease Patients: A Systematic Review
TLDR
This review evaluates the main studies about the safety food in CD patients and concludes that the absence of gluten in natural and processed foods represents a key aspect of food safety of the gluten-free diet. Expand
Coeliac disease
TLDR
Difficulties adhering to a gluten-free diet have led to the development of non-dietary therapies, several of which are undergoing trials in human beings. Expand
Celiac disease: Role of genetics and immunity and update on novel strategies for treatment
TLDR
The purpose of this review is to highlight the complex involvement of genetics and immunity in CD and to focus on the novel strategies being used for developing adjunct and alternative therapies for the treatment of CD. Expand
Celiac disease among children and adolescents.
  • M. Mearin
  • Medicine
  • Current problems in pediatric and adolescent health care
  • 2007
TLDR
Celiac disease was once thought to be a rare condition, but at the present time it is accepted that CD is the most common form of food hypersensitivity in children and adults. Expand
Celiac disease: epidemiology, pathogenesis, diagnosis, and nutritional management.
TLDR
Therapy of CD is a lifelong gluten-free diet and Counseling by an expert dietitian and association with a celiac support group are important in helping the patient embark on a healthy gluten- free diet. Expand
Diagnosing coeliac disease: A literature review.
TLDR
This review examines the pathogenesis and diagnosis of coeliac disease and considers novel and innovative biomarkers in its diagnosis specifically in an African population. Expand
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