Corpus ID: 26560220

Codominant and recessive 9-beta-D-arabinofuranosyladenine-resistant mutations of baby hamster cells.

@article{Chan1985CodominantAR,
  title={Codominant and recessive 9-beta-D-arabinofuranosyladenine-resistant mutations of baby hamster cells.},
  author={V. Chan and S. Guttman},
  journal={Mutation research},
  year={1985},
  volume={149 1},
  pages={
          141-6
        }
}
9-beta-D-Arabinosyladenine (araA)-resistant mutants of baby hamster kidney (BHK) cells can be classified into 3 classes. In order to gain a better understanding of the mechanism(s) of resistance and the biochemical basis of cytotoxicity of various purine nucleosides, cell hybrids of the mutant and wild-type cells were made and analyzed. The class I araA-resistant, adenosine-kinase-deficient (AK-) allele was shown to be recessive to the wild-type araA-sensitive (AK+) gene. The class II mutant… Expand
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