Coculture with cumulus cells improves maturation of mouse oocytes denuded of the cumulus oophorus: observations of nuclear and cytoplasmic events.

@article{Ge2008CocultureWC,
  title={Coculture with cumulus cells improves maturation of mouse oocytes denuded of the cumulus oophorus: observations of nuclear and cytoplasmic events.},
  author={Li hong Ge and Hong-Shu Sui and G. Zhiyong Lan and Na Liu and J Wang and Jing-He Tan},
  journal={Fertility and sterility},
  year={2008},
  volume={90 6},
  pages={2376-88}
}
OBJECTIVE To study the mechanisms by which cumulus cells (CCs) promote oocyte maturation by observing the effect of removing the cumulus oophorus on nuclear and cytoplasmic events during in vitro maturation. DESIGN Experimental animal study. SETTING Academic institution. ANIMAL(S) Mice of the Kun-ming breed. INTERVENTION(S) Cumulus-free oocytes were cultured alone (DOs) or with a CC monolayer (coDOs), and the nuclear and cytoplasmic events were compared with those of oocytes matured in… CONTINUE READING
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