Cocoa and Dark Chocolate Polyphenols: From Biology to Clinical Applications

@article{Magrone2017CocoaAD,
  title={Cocoa and Dark Chocolate Polyphenols: From Biology to Clinical Applications},
  author={Thea Magrone and M. Russo and E. Jirillo},
  journal={Frontiers in Immunology},
  year={2017},
  volume={8}
}
It is well known that cocoa and dark chocolate possess polyphenols as major constituents whose dietary consumption has been associated to beneficial effects. In fact, cocoa and dark chocolate polyphenols exert antioxidant and anti-inflammatory activities switching on some important signaling pathways such as toll-like receptor 4/nuclear factor κB/signal transducer and activator of transcription. In particular, cocoa polyphenols induce release of nitric oxide (NO) through activation of… Expand
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