Cochlin expression in anterior segment organ culture models after TGFbeta2 treatment.

@article{Bhattacharya2009CochlinEI,
  title={Cochlin expression in anterior segment organ culture models after TGFbeta2 treatment.},
  author={Sanjoy K Bhattacharya and B'ann T Gabelt and Jos{\'e} Ru{\'i}z and Renata Picciani and Paul L. Kaufman},
  journal={Investigative ophthalmology & visual science},
  year={2009},
  volume={50 2},
  pages={551-9}
}
PURPOSE To determine the effect of transforming growth factor (TGF)-beta2 treatment on intraocular pressure (IOP), outflow facility, and cochlin expression in vitro in monkey and pig organ-cultured anterior segments (MOCAS and POCAS). METHODS MOCAS (rhesus and cynomolgus) or POCAS were infused with media containing 10 ng/mL TGFbeta2 to one segment of each pair and 0.1% BSA (vehicle) to the contralateral segment for up to 14 days at a constant rate. Cochlin expression was determined by… CONTINUE READING

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Anatomy and physiology of aqueous humor outflow

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Highly Influential
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