Cochlear function in mice lacking the BK channel alpha, beta1, or beta4 subunits.

@article{Pyott2007CochlearFI,
  title={Cochlear function in mice lacking the BK channel alpha, beta1, or beta4 subunits.},
  author={Sonja J Pyott and Andrea L Meredith and Anthony Fodor and Ana Elena V{\'a}zquez and Ebenezer N. Yamoah and Richard W. Aldrich},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 5},
  pages={3312-24}
}
Large conductance voltage- and calcium-activated potassium (BK) channels are important for regulating many essential cellular functions, from neuronal action potential shape and firing rate to smooth muscle contractility. In amphibians, reptiles, and birds, BK channels mediate the intrinsic frequency tuning of the cochlear hair cell by an electrical resonance mechanism. In contrast, inner hair cells of the mammalian cochlea are extrinsically tuned by accessory structures of the cochlea… CONTINUE READING
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