Cocaine self-administration in Wistar-Kyoto rats: a behavioral and biochemical analysis.


Depression and cocaine abuse disorders are common concurrent diagnoses. In the present study, we employed Wistar-Kyoto (WKY) rats that showed a depressive-like phenotype to study intravenous cocaine self-administration and extinction/reinstatement procedures. We also investigated the basal tissue level of neurotransmitters, their metabolites and plasma… (More)
DOI: 10.1016/j.bbr.2015.06.040