Cocaine reward and hyperactivity in the rat: Sites of mu opioid receptor modulation

@article{Soderman2008CocaineRA,
  title={Cocaine reward and hyperactivity in the rat: Sites of mu opioid receptor modulation},
  author={Avery R. Soderman and Ellen M. Unterwald},
  journal={Neuroscience},
  year={2008},
  volume={154},
  pages={1506-1516}
}
Opioid receptor agonists and antagonists have profound effects on cocaine-induced hyperactivity and conditioned reward. Recently, the role specifically of the mu opioid receptor has been demonstrated based on the finding that i.c.v. administration of the selective mu opioid receptor antagonist, D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP), can attenuate cocaine-induced behaviors. The purpose of the present study was to determine the location of mu opioid receptors that are critical for… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 52 references

A role for mu opioid receptors in cocaineinduced activity, sensitization, and reward in the rat

JA chroeder, M Hummel, +3 authors EM Unterwald
Psychophar - macology ( Berl ) • 2007

Altered prelimbic cortex output during cue-elicited drug seeking.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2004

Effect of experimenter-delivered and self-administered cocaine on extracellular beta-endorphin levels in the nucleus accumbens

I oth-Deri, A Zangen, +7 authors G Yadid
J Neurochem • 2003

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